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A Study on Life Changes of Oral Lichen Planus Patients by SRRS

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¿Á¼ö¹Î ( Ok Soo-Min ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
ÇãÁØ¿µ ( Heo Jun-Young ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
¾È¿ë¿ì ( Ahn Yong-Woo ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç
Á¤¼ö¹Î ( Jeong Su-Min ) - ºÎ»ê´ëÇб³ Ä¡ÀÇÇÐÀü¹®´ëÇпø ±¸°­³»°úÇб³½Ç

Abstract

ÆíÆòż±Àº ÇÇºÎ¿Í Á¡¸·¿¡ ¹ß»ýÇÏ´Â ¸¸¼º ¿°Áõ¼º ÁúȯÀ¸·Î½á ½Åü ¿©·¯ ºÎÀ§¿¡ ħ¹üÇÏ¿© ¸Å¿ì ´Ù¾çÇÑ ÀÓ»ó¼Ò°ßÀ» ³ªÅ¸³½´Ù. ¾ÆÁ÷ Á¤È®ÇÑ ¿øÀÎÀº ¹àÇôÁöÁö ¾Ê¾ÒÀ¸³ª ÇǺγª Á¡¸·¿¡¼­ À¯µµµÈ Ç׿øº¯È­¿¡ ´ëÇÑ »óÇÇ¿Í °áüÁ¶Á÷ »çÀÌÀÇ ¼¼Æ÷¸Å°³¼º ¸é¿ª¹ÝÀÀ¿¡ ÀÇÇÑ °ÍÀ¸·Î ¾Ë·ÁÁ® ÀÖ´Ù. Á߳⠿©¼º¿¡¼­ È£¹ßÇÏ°í, Áõ»óÀÇ ¾ÇÈ­¿Í ¿ÏÈ­°¡ ¹ø°¥¾Æ ÀϾ´Â °ÍÀÌ ÀÌ ÁúȯÀÇ Æ¯Â¡À¸·Î, Á¤½ÅÀû ½ºÆ®·¹½º, À¯ÀüÀû ¿äÀÎ, ȯ°æÀû ¿äÀÎ, ¾à¹° µîÀÇ ¿©·¯ ¿ä¼Ò°¡ Áõ»óÀÇ ¾ÇÈ­¿¡ °ü¿©ÇÏ´Â °ÍÀ¸·Î ÃßÁ¤µÈ´Ù. ÇǺΠÆíÆòż± ȯÀÚÀÇ 60-70%¿¡¼­ ±¸°­ ÆíÆòż±ÀÌ µ¿¹ÝµÇ°í, ±¸°­ ÆíÆòż± ȯÀÚÀÇ 2/3 °¡·®ÀÌ ´Üµ¶º´¼Ò·Î½á ³ªÅ¸³­´Ù. À̹ø ¿¬±¸¿¡¼­´Â Á¤¼­Àû ½ºÆ®·¹½º°¡ ±¸°­ ÆíÆòż±À» ¾ÇÈ­½ÃÅ°´Âµ¥ ÀÖ¾î ¾î¶² ¿µÇâÀ» ¹ÌÄ¡´ÂÁö Æò°¡ÇÏ°íÀÚ ÇÑ´Ù. ÀÓ»ó°Ë»ç ȤÀº Á¶Á÷°Ë»ç °á°ú ±¸°­ ÆíÆòż±À¸·Î Áø´ÜµÈ ȯÀÚ 30¸í°ú Ä¡°ú´ëÇÐ ÇлýµéÀÇ ºÎ¸ðµé Áß ±¸°­ ÆíÆòż±ÀÇ Áõ»ó ¹× º´·ÂÀÌ ¾ø´Â 30¸íÀ» ´ë»óÀ¸·Î ÇÏ¿´´Ù. ½ºÆ®·¹½º »óȲÀÇ Æò°¡¸¦ À§Çؼ­´Â Çѱ¹Àû ¹®È­¿¡ ¸Â°Ô ÀûÀýÇÏ°Ô º¯ÇüÇÑ Holmes¿Í RaheÀÇ »çȸÀû ÀçÀûÀÀ ÆòÁ¤Ã´µµ ¼³¹®Áö(SRRS)¸¦ ÀÌ¿ëÇÏ¿´´Ù. ºÐ¼®°á°ú ±¸°­ ÆíÆòż± ȯÀÚµéÀÌ ´ëÁ¶±º¿¡ ºñÇØ ÃÖ±Ù 1³â µ¿¾È ´õ ¸¹Àº ¼öÀÇ ½ºÆ®·¹½º¼º »ç°ÇµéÀ» °æÇèÇÑ °ÍÀ¸·Î ³ªÅ¸³µ´Ù.

Lichen planus is a chronic inflammatory mucocutaneous disease that affects multiple sites of the body. Often it involves the oral mucosa, but also involve other sites such as skin, genitals, scalp and nails. There is no clear cause of oral lichen planus (OLP), current data suggest that OLP is a T-cell mediated autoimmune disorder which may have an altered self-peptide triggering apoptosis of oral epithelial cells. Usually OLP appears in middle-aged women which tends to be chronic with periods of exacerbation and remission. There are many theories those causes the OLP such as psychological and environmental factors, genetic tendency, drugs and more. 60-70% of lichen planus is accompanied by oral lesions, and more than half of its cases are not able to defined by their skin. In this study, among all the possibility(possible) theories, we tried to evaluate the influence of emotional stress in exacerbating OLP. There were thirty patients with a clinical or histological diagnosis of OLP and other thirty subjects who did not show any signs of systemic disorders include OLP. They were evaluated by using modified Holmes and Rahe¡¯s Social Readjustment Rating Scale (SRRS). As a result, a significantly higher level of stress was found in the OLP patients than the control group. Therefore it could be concluded that psychological stressors play an important role in the exacerbating OLP.

Å°¿öµå

±¸°­ ÆíÆòż±; »çȸÀû ÀçÀûÀÀ ÆòÁ¤Ã´µµ; ½ºÆ®·¹½º¼º »ýÈ°»ç°Ç
Oral lichen planus; Social readjustment rating scale (SRRS); Stressful life events

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